Laboratoire Sciences et Méthodes Séparatives

University of Rouen Normandy - Normandie Université – SMS EA 3233

• Y. Cartigny, J.M. Fiorani, A. Maître, M. Vilasi, « Thermodynamic assessment on the Pb–Ca–Sn ternary system », Intermetallics, Vol. 11, n° 11-12 (2003) 1205-1210.

  Y. Cartigny, J.M. Fiorani, A. Maître, M. Vilasi, « Thermodynamic assessment of the Ca–Pb system », Thermochimica Acta, Vol. 414, n° 2 (2004) 197-202.

  Y. Cartigny, J.M. Fiorani, A. Maître, M. Vilasi, « Thermodynamic assessment on the Ca–Sn system », Zeitschrift für Metallkunde, n°11, 1308-1313.

  N.David, Y. Cartigny, T. Belmonte, J.M. Fiorani, M. Vilasi, « Thermodynamic description of the Cr-Nb-Si isothermal section at 1473 K », Intermetallics, Vol 14, n°4,  (2006) 464-473.

  Y. Cartigny, J.M. Fiorani, A. Maître, M. Vilasi,  « Pb-based composite materials for grids of acid battery », Materials Chemistry and Physics, Vol 103 n°2-3  (2007) 270-277.

  Y. Cartigny, J. Ravaux, L. Aranda, J.M. Fiorani and M. Vilasi, « The Pb-Ca-Sn system: experimental investigations for x(Ca)≤ 0.25 composition and thermodynamic modelling », Journal of Power Sources, vol 177, n°2 (2007) 925-932.

  Y. Cartigny, J.M. Fiorani, A. Maître, M. Vilasi, « Contribution of the associated complex in binary liquid to model the Ca-Pb-Sn ternary system», Journal of Non Crystalline Solids 353 (2007) 3727-3732

  F. Querniard, J. Linol, Y. Cartigny, G. Coquerel, « Study of the quaternary system (+) and (–)5-phenyl-5-trifluroromethyl-imidazolidine-2,4-dione / (–)1-phenyl-ethylamine/Ethanol  at 20°C under atmospheric pressure”, Journal of thermal analysis and calorimetry; Vol 90 (2007) 359-365.

  L. Renou, S. Coste, Y. Cartigny, M-N Petit, C. Vincent, J-M Schneider, G. Coquerel , « Mechanism of hydration and dehydration of ciclopirox ethanolamine (1.1) », Crystal Growth and Design, vol 9 (2009) 3918-3927.

  G. Descamps, Y. Cartigny, M. Sanselme, M-N Petit, S. Petit, E. Aubin G. Coquerel, « Structural and physicochemical characterization of a solid solution produced by antisolvent crystallization of a new phosphoantigen », Crystal Growth and Design, vol.9 (2009) 3910-3917.

  N. Couvrat, A.S. Blier, B. Berton, Y. Cartigny, V. Dupray, G. Coquerel, « Characterization of defects inside single crystals of ciclopirox», Crystal Growth and Design, vol 9 (2009) 2719-2724.

  Y. Amharar, S. Petit, M. Sanselme, Y. Cartigny, M-N Petit, G. Coquerel, “ Crystal Structures, Dehydration Mechanism, and Chiral Discrimination in the Solid State of a Hydantoin Derivative”, Crystal Growth & Design, vol 11 (2011), 2453-2462.

  A. Lafontaine, M. Sanselme, Y. Cartigny, P. Cardinael, G. Coquerel, Charactherization of the transition between the monohydrate and the anhydrous citric acid, Journal of Thermal Analysis and Calorimetry, vol 112 (2013), 307-315.

  N. Couvrat, A. Burel, S. Tisse, Y. Cartigny, G. Coquerel, Combining Zone melting and preparative chromatography to purify phenanthrene, Journal of Thermal Analysis and Calorimetry, vol 112 (2013), 293-300.

  Y. Cartigny, G. Coquerel, “Special Chapter : Advanced Thermal Science in France”, Journal of Thermal Analysis and Calorimetry, vol 112 (2013), 211-213.

  Y. Cartigny, G. Coquerel, “Impact of Solid / Vapour Equilibria on Conditions of Crystallization of Pharmaceutical Compounds” Transactions of Tianjin University (2013) 19 (1), 53-57.

  R. Rotival, Y. Corvis, Y. Cartigny, P. Negrier, M. Marchivie, S. Massip, I. Gana, P. Lemoine, P. Espeau, « Comprehensive Determination of the Solid State Stability of Bethanechol Chloride Active Pharmaceutical Ingredient using Combined Analytical Tools” Cryst. Eng. Comm (2013) 15, 7970-7980.

  C. Brandel, Y. Amharar, Y. Cartigny, S. Petit, G. Coquerel, J. Rollinger, U. Griesser, “Impact of molecular flexibility on double polymorphism, solid solutions and chiral discrimination during crystallization of diprophylline enantiomers”, Molecular Pharmaceutics (2013), 10(10), 3850-3861.

  N. Couvrat, A. Burel, S. Tisse, Y. Cartigny, G. Coquerel. « Combining zone melting and preparative chromatography to purify Phenanthrene “, Journal of Thermal Analysis and Calorimetry, Springer Verlag, 2013, 112 (1), pp.293 - 300.

  C. Brandel,  G. Gbabode, Y. CARTIGNY, C. Martin, G. Gouhier, S.Petit, G. Coquerell  « Crystal Growth, Structure and Polymorphic Behavior of an Ionic Liquid: Phthalate Derivative of N-butyl,N-methylimidazolium Hexafluorophosphate » Chemistry of materials (2014), 26 (14), 4151-4162.

  B. Fours, Y. Cartigny, S. Petit, G. Coquerel, “Formation of New Polymorphs Without any Nucleation Step : Desolvation of the Rimonabant Monohydrate: Directional Crystallisation Concomitant to Smooth Dehydration”, Faraday discussion (2015), 179, 475-488

  N. Couvrat, Y. Cartigny, J. Linol, L. Vaysse-Ludot, P. Langlois, G. Coquerel, « Crystallization of Terutroban Sodium Salt Hydrate from the Deliquescent State” Chemical Engineering and technology (2015) 38, 6, 999-1005

  G. Coquerel, N. Couvrat, Y. Cartigny, « Industrial Crystallization », Chemical Engineering and technology (2015), 38, 6, 967.

  C. Brandel, Y. Cartigny, N. Couvrat, M. Ermelinda S. Eusebio, J. Canotilho, S. Petit, G. Coquerel, « Mechanisms of Reversible Phase Transitions in Molecular Crystals: Case of Ciclopirox”, Chemistry of materials (2015), 27 (18), 6360-6373

  C. Neurohr, M. Marchivie, S. Lecomte, Y. Cartigny, N. Couvrat, M. Sanselme, P. Subra-Paternault, « Naproxen–Nicotinamide Cocrystals: Racemic and Conglomerate Structures Generated by CO2 Antisolvent Crystallization, Crystal Growth & Design (2015), 15 (9), 4616-4626

  Lina Yuan, Simon Clevers, Nicolas Couvrat, Yohann Cartigny, Valerie Dupray et al.  “Precise Urea/Water Eutectic Composition by Temperature-Resolved Second Harmonic Generation”, Chemical Engineering and Technology, Wiley-VCH Verlag, 2016, 39 (7), pp.1326 - 1332.

  Antoine Burel, Sander Brugman, Mélanie Mignot, Yohann Cartigny, Séverine Tisse et al. “Phenanthrene Purification: Comparison of Zone Melting and Co-Crystallization”, Chemical Engineering and Technology, Wiley-VCH Verlag, 2016, 39 (7), pp.1317 - 1325.

  Clément Brandel, Yohann Cartigny, Gérard Coquerel, Joop Ter horst, Samuel Petit. “Prenucleation Self-Assembly and Chiral Discrimination Mechanisms during Solution Crystallisation of Racemic Diprophylline”, Chemistry - A European Journal, Wiley-VCH Verlag, 2016, 22 (45), pp.16103 - 16112

  Clément Brandel, Samuel Petit, Yohann Cartigny, Gérard Coquerel. « Structural Aspects of Solid Solutions of Enantiomers”, Current Pharmaceutical Design, Bentham Science Publishers, 2016, 22 (32), pp.4929 - 4941.

  Nicolas Couvrat, Julien Mahieux, Baptiste Fours, Yohann Cartigny, Eric Schenkel et al.  « Impact of sodium chloride on the expansion of a liquid-liquid miscibility gap in an API/water system. Case study of Brivaracetam”, International Journal of Pharmaceutics, Elsevier, 2016, 515 (1-2), pp.702 - 707.

  Théo Henriet, Inès Gana, Carine Ghaddar, Maria Barrio, Yohann Cartigny et al.  « Solid state stability and solubility of triethylenetetramine dihydrochloride”, International Journal of Pharmaceutics, Elsevier, 2016, 511 (1), pp.312 - 321.

  Quentin Viel, Clément Brandel, Yohann Cartigny, M. Ermelinda S. Eusébio, João Canotilho et al.  « Crystallization from the Amorphous State of a Pharmaceutical Compound: Impact of Chirality and Chemical Purity”, Crystal Growth and Design, American Chemical Society, 2017, 17 (1), pp.337 - 346.

  Antoine Burel, Nicolas Couvrat, Séverine Tisse, Yohann Cartigny, Pascal Cardinaël et al.  « Binary phase diagrams between phenanthrene and two of its impurities: 9,10-dihydroanthracene and carbazole”, European Physical Journal - Special Topics, EDP Sciences, 2017, 226 (5), pp.869 - 880.

  Aurélien Lemercier, Quentin Viel, Clément Brandel, Yohann Cartigny, Eric Dargent et al. « Optimization of experimental conditions for the monitoring of nucleation and growth of racemic Diprophylline from the supercooled melt”, Journal of Crystal Growth, Elsevier, 2017, 472, pp.11 - 17

  Antoine Burel, Marie Vaccaro, Yohann Cartigny, Séverine Tisse, Gérard Coquerel et al.  « Retention modeling and retention time prediction in gas chromatography and flow-modulation comprehensive two-dimensional gas chromatography: The contribution of pressure on solute partition”, Journal of Chromatography A, Elsevier, 2017, 1485, pp.101 - 119.

  Lina Yuan, Elena Horosanskaia, Felix Engelhardt, Frank Edelmann, Nicolas Couvrat et al.  « Solvate Formation of Bis(demethoxy)curcumin: Crystal Structure Analyses and Stability Investigations”, Crystal Growth and Design, American Chemical Society, 2019, 19 (2), pp.854-867.

  Nicolas Couvrat, Morgane Sanselme, Yohann Cartigny, Frederic de Smet, Sandrine Rome et al.  “A Possible Infinite Number of Components in a Single Crystalline Phase: On the Isomorphism of Brivaracetam–Guest Molecules”, Crystal Growth and Design, American Chemical Society, 2018, 18 (9), pp.4807 - 4810.

  N. Couvrat, Y. Cartigny, “Special Chapter : Industrial Crystallization”, Chemical Engineering and technology 2019,42,7,1427

  M. Schindler, Nicolas Couvrat, Yohann Cartigny, Clément Brandel, Gérard Coquerel. “Synthesis and Characterization of sodium dithionate and its dihydrate”, Chemical Engineering and Technology, Wiley-VCH Verlag, 2019

  Lina C. Harfouche, Clément Brandel, Yohann Cartigny, Joop H. Ter Horst, Gérard Coquerel, Samuel Petit, “Enabling Direct Preferential Crystallization in a Stable Racemic Compound System”, Molecular Pharmaceutics, 2019, 16, 11, 4670–4676

  Lina C. Harfouche, Clément Brandel, Yohann Cartigny, Samuel Petit,Gérard Coquerel, « Resolution by Preferential Crystallization of Proxyphylline by Using Its Salicylic Acid Monohydrate Co‐Crystal”, Chemical Engineering & Technology Volume 43, Issue 6, 1093-1098

  Lina C. Harfouche, Nicolas Couvrat, Morgane Sanselme, Clément Brandel, Yohann Cartigny, Samuel Petit, and Gérard Coquerel, « Discovery of New Proxyphylline-Based Chiral Cocrystals: Solid State Landscape and Dehydration Mechanism”, Cryst. Growth Des. 2020, 20, 6, 3842–3850

  Aliou Mbodji, Gabin Gbabode, Morgane Sanselme, Yohann Cartigny, Nicolas Couvrat, Michel Leeman, Valérie Dupray, Richard M. Kellogg, and Gérard Coquerel, “Evidence of Conglomerate with Partial Solid Solutions in Ethylammonium Chlocyphos”, Cryst. Growth Des. 2020, 20, 4, 2562–2569

  Romain Rotival, Stéphane Massip, Yohann Cartigny, Philippe Négrier, Yohann Corvis, and Philippe Espeau,”Characterization of Unknown Solid States of the Drug Substance Quinacrine Dihydrochloride: Two Anhydrous Forms and a Tetrahydrate Revealed”, Cryst. Growth Des. 2020, 20, 8, 5261–5268

Patent :

N. Couvrat, M.N. Petit, Y. Cartigny, G. Coquerel, F. Balavoine, J. Madec, J.M. Schneider, “Method for the preparation of (3S,3S’) 4,4’-disulfanediylbis(3-aminobutane 1-sulfonic acid)”,WO/2012/045849, PCT/EP2011/067524