Photo

Mme. Valérie DUPRAY
Assistant Professor - HDR

44 y.o.

+33 2 32 39 90 82 / +33 2 35 52 24 09
valerie.dupray@univ-rouen.fr

Laboratoire SMS
Place Emile Blondel
76821 Mont-Saint-Aignan CEDEX
France

 

Education
2013      HDR  (Accreditation to supervise research - with honors)– Normandie Université
 Development of optical methods for the characterization of crystallized organic compounds
 
1999  PhD in Physic (with high honors) - Normandie Université
Photorefractive effect in InP:Fe crystals for applications to commutation optics
 
1995                      Master of Physics – Normandie Université
Work Experience

2000- Today         Assistant then Associate Professor
Normandie Université - Université de Rouen
UFR Sciences et Techniques / SMS EA 3233 (Director : Prof. G. Coquerel)

1999-2000           Post-Doctoral position (12 months), Imperial College of London, Applied Optics Group
(Director : Prof. C. DAINTY)

1998-1999           Lecturer, Normandie Université – Université de Rouen
UFR Sciences et Techniques / UMR 6614- CORIA – Optics and Optronics Group (Director : Prof. C. Özkul)

Papers
h-index : 8 ; 1 Book chapter
33 Publications on refereed journals
303 Citations for refereed papers
 
  1. Yuan, L. N., Clevers, S.,  Couvrat, N.,  Cartigny, Y., Dupray, V.œ and Coquerel, G. (2016). Precise Urea/Water Eutectic Composition by Temperature-Resolved Second Harmonic Generation, Chemical Engeeniering & Technology, 39, In Press
  2. Schammé, B., Couvrat, N., Malpeli, P., Dudognon, E., Delbreilh, Dupray, V.œ, Dargent, E. and Coquerel, G. (2016). Transformation of an active pharmaceutical ingredient upon high-energy milling: A process-induced disorder in Biclotymol. International Journal of Pharmaceutics 499 (1–2), 67-73.
  3. Schammé, B., Couvrat, N., Malpeli, P., Delbreilh œ, L., Dupray, V.œ, Dargent, E. and Coquerel, G. (2015). Crystallization kinetics and molecular mobility of an amorphous active pharmaceutical ingredient: A case study with biclotymol. International Journal of Pharmaceutics, 490 (1-2), 248–257
  4. Simon, F., Clevers, S., Gbabode, G., Couvrat, N., Agasse-Peulon, V., Sanselme, M., Dupray, V.œ, and Coquerel, G. (2015). Enhanced second harmonic generation from organic self-assembled eutectic binary mixture: A case study with 3-nitrobenzoic and 3,5-dinitrobenzoic acids. Crystal Growth & Design, 15 (2),  946–960
  5. Simon, F.*, Clevers, S.*, Dupray, V.œ and Coquerel, G. (2015). Relevance of second Harmonic Generation to characterize crystalline Samples, Review Article, Chemical Engineering & Technology, 38(6), 971-983. *: equal contributors
  6. Clevers, S., Simon, F., Sanselme, M., Dupray, V.œ and Coquerel, G. (2013). Monotropic transition mechanism of m-hydroxybenzoic acid investigated by Temperature Resolved Second Harmonic Generation, Crystal Growth & Design, 13(8), 3697-3704.
  7. Clevers, S., Simon, F., Dupray, V.œ and Coquerel, G. (2013). Temperature resolved second harmonic generation to probe the structural purity of m-hydroxybenzoic acid. Journal of Thermal Analysis and Calorimetry, 112(1), 271-277.
 
  1. Waldschmidt, A., Couvrat, N., Berton, B, Dupray, V., Morin S., Petit, S., and Coquerel, G. (2011). Impact of gas composition in the mother liquor on the formation of macroscopic inclusions and crystal growth rates. A case study with ciclopirox crystals. Crystal Growth & Design, 11 (6), 2463-2470.
  2. Dupray, V.œ, Berton, B., Ossart, S., Atmani, H., Petit, MN. and Coquerel, G. (2009). Concomitant Dehydration Mechanisms in Single Crystals of Trehalose, Carbohydrate Research, 344, 2539-2546.
  3. Galland, A., Dupray, V.œ, Berton, B.,Morin-Grognet, S.,Sanselme, M., Atmani, H. and Coquerel, G. (2009). Spotting Conglomerates by Second Harmonic Generation, Crystal Growth & Design, 9(6), 2713-2718.
Symposium Participation
Communications Orales
  1. —Clevers, S., Yuan, L.N., Dupray, V., Coquerel, G., Formic Acid (FA)-Water Phase Diagram by means of temperature-resolved second harmonic generation and FA phase transition : A reinvestigation, BIWIC 2016, 22th International Workshop on Industrial Crystallization September 6-8, 2016, Magdeburg, Germany
  2. — Yuan, L. N., Clevers, S., Baaklini, G., Couvrat, N., Cartigny, Y.,  Dupray, V., Coquerel, G., Metastable eutectic composition determination of 1, 3-dimethylurea/water system by temperature-resolved second harmonic generation (TR-SHG), ACTS 2016, Asian Crystallization Technology Symposium 2016, May 25-27, 2016, Tainjin, China
  3. —Couvrat, N., Sanselme, M.,  Dupray, V., Taulelle, P., Lerestif, J.M.,   Lynch, M., Vaysse-Ludot, L. and  Coquerel, G., Partial Blockage of the reversible solid-solid transition of strontium succinate, BIWIC 2015, 21th International Workshop on Industrial Crystallization, September 9-11 , 2015, Deajeon, Korea
  4. —Schammé, B. , Couvrat, N., Delbreilh, L., Couvrat, N., Dupray, V., Coquerel, G., Role of Molecular Mobility on Physical Stability : Case study of two Amorphous Pharmaceuticals in the Supercooled and Glassy States, PolyChar 23, May 11-15, 2015, University of Nebraska-Lincoln, Lincoln, Nebraska, U.S.A.
  5. —Baaklini, G. ,  Dupray, V., and  Coquerel, G. Effect of urea derivatives in blocking the metastable form of pirazinamide by co-spray drying, JEEP 2015- 41th Conference on Phase Equilibria, March 25-27, 2015, Coimbra, Portugal
  6. —Schammé, B. , Delbreilh, L., Couvrat, N., Dupray, V., Coquerel, G., Thermal and physical stability of amorphous Biclotymol, Condensed Mater in Paris- CMD25/JMC14, August 24-29 , 2014, Paris, France
 
Posters
  1. Yuan, L.N., Clevers, S., Couvrat, N., Dupray, V. and Coquerel, G. Investigations on 2-adamantanone low temperature phase transition by temperature-resolved second harmonic generation, 12 th International Workshop of the Crystal Growth of Organic Material & 47th Annual British Association of Crystal Growth Conference Joint Conference, 26th – 30th June, 2016, University of Leeds, UK
  2. Yuan, L., Clevers, S., Couvrat, N., Dupray, V. and Coquerel, G. Urea/water Phase Diagram Investigation thought Temperature-Resolved Second Harmonic Generation (TR-SHG), BIWIC 2015 – 22th Bremen International Workshop on Industrial Crystallization, September 9-11, 2015, Deajeon, Korea
  3. Yuan, L., Clevers, S., Couvrat, N., Dupray, V. and Coquerel, G. Urea/water Phase Diagram Determination by Means of Temperature-Resolved Second Harmonic Generation (TR-SHG), JEEP 2015 - 41st  Conference on Phase Equilibria, March 25-27, 2015, Coimbra, Portugal
  4. Simon, F., Clevers, S., Brandel, C., Mahieux, J., Dupray, V. and Coquerel, G. Relevance of second harmonic generation (SHG) in material Science studies – Part 1: Literature review and experimental methods, BIWIC 21 – 11th Bremen international workshop on industrial crystallization, September 10-12, 2014, Rouen France
Scientific Skills
Thermal Analysis (DSC – TG-DSC) – Interpretation
Microscopy (optical, electronic)
Development of Experimental Prototypes (préciser)
Solution Crystallization (polymorphism control, crystal engineering, salt, co-crystals)
Particle Size Distribution evaluation (Malvern PSD)
Spectroscopy (Raman, Infra-rouge, UV-vis, fluorescence)
Amorphous state characterization (thermal analysis / Broadband Dielectric Spectroscopy)
Solid-state characterization (polymorphism, solvates, cocrystals, solid-solid transition)
Optics and non linear optics
Second Harmonic Generation
Second Harmonic Generation (temperature resolved)