Ms Laureline MARC
PhD Student (Year 2)


02 35 14 63 50

Laboratoire SMS
Place Emile Blondel
76821 Mont-Saint-Aignan CEDEX


PhD Thesis

Continuous Crystallization - Development of new technologies for continuous crystallization of organic molecules intended for the field of fine chemistry

Supervised by Pr. G. Coquerel (SMS) and Dr. J.-M. Schneider (Seqens Porcheville)

CIFRE funding with SEQENS company

Date of defense previsional : 2022

  • 2017-2018 Master’s Degree in Chemistry specialised in Crystallization, Rouen Normandy University, France
  • 2014-2017 « Ingénieur Chimiste » Diploma (equivalent to a top Master’s Degree in Chemistry), ENSCM-Ecole Nationale Supérieure de Chimie de Montpellier (National Graduate School of Chemistry of Montpellier), France
    • Erasmus exchange program (09/2016 – 02/2017) in a Master’s Degree training in Chemical Engineering, Universidad Complutense de Madrid, Spain
  • 2012-2014 DUT Chimie (Technological Degree in Chemistry), IUT Chimie de Grenoble (University Institute of Technology of Chemistry of Grenoble), France
Work Experience
  • 2018-2019 Crystallization Scientist, Crystallization and Solid State Unit, Seqens, Porcheville, France
  • 2014-2017 R&D Chemist in apprenticeship, Sanofi
    • Physical Quality Laboratory, Montpellier, France (2016-2017)
    • Pre-Development Laboratory, Waltham, MA, USA (2016)
    • Process Safety Laboratory, Montpellier, France (2014-2015)
  • 2013-2014 Laboratory Technician in apprenticeship, Chemical Analysis and Characterization Laboratory, Constellium, Voreppe, France
Symposium Participation
  • Poster Presentation :

Laureline Marc, Jean-Marie Schneider and Gérard Coquerel, "Continuous chiral resolution by diastereomeric salt formation of racemic Ibuprofen in a Couette-Taylor crystallizer", Journées Nationales Réseau Cristech (CNRS), October 14-16th  2020, Ecully (69), France

Scientific Skills
Thermal Analysis (DSC – TG-DSC) – Implementation
Thermal Analysis (DSC – TG-DSC) – Interpretation
XRay Powder diffraction - user
Phase Diagram - Experimental Determination
Microscopy (optical, electronic)
Chiral Resolution by Crystallization
Development of Experimental Prototypes (préciser)
Solution Crystallization (polymorphism control, crystal engineering, salt, co-crystals)
Particle Size Distribution evaluation (Malvern PSD)
NMR spectroscopy
Solid-vapour equilibria (DVS)
Solid-state characterization (polymorphism, solvates, cocrystals, solid-solid transition)