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Mr. Clément Brandel 26 juillet 1988 02 35 52 29 02 |
Laboratoire SMS |
2011-2014 : Doctorate of Chemistry at the University of Rouen, Laboratoire Sciences et Méthodes Séparatives (SMS), EA3233. « Structural Purity and Solid-Solid Transitions in Molecular Crystals », defended in English 07th November 2014.
2010-2011: Master 2 Material Physics, University of Rouen
2009-2010: Master 1 Chemistry, University of Rouen
2006-2009: Bachelor Degree in Chemistry, University of Rouen
2006: French Secondary School Diploma, Science
2014-2015 : Senior Particle Scientist at GlaxoSmithKline (UK)
2011-2014: European Doctorate
Jan 2014: Reasearch Training Period (6 weeks) at the « Process & Energy Laboratory », TU Delft, Delft, Pays-Bas
Jul 2013: Reasearch Training Period (6 weeks) in the Department of Chemistry of the University of Coimbra, Portugal
2011: Master 2 Reasearch Training Period (6 months) in the Laboratoire Sciences et Méthodes Séparatives (SMS), EA3233of the University of Rouen
2009: Bachelor Reasearch Training Period (3 months) at Polyintell, Val de Reuil, France.
C. Brandel, Y. Cartigny, G. Coquerel, J.H. ter Horst, S. Petit “Prenucleation Self-Assembly and Chiral Discrimination Mechanisms during Solution Crystallization of Racemic Diprophylline” Chem. Eur. J., 2016, published ASAP (10.1002/chem.201602707).
C. Brandel, S. Petit, Y. Cartigny, G. Coquerel “Structural Aspects of Solid Solutions of Enantiomers” Cur. Pharm. Des., 2016, published ASAP (10.2174/1381612822666160720164230).
C.Brandel, J. W. B. Cooke, R. A. J. Horan, F. Mallet, D. R. Stevens “Optimization of the Preparation of (R)-3,5-Bis(trifluoromethyl)-α-methyl-N-methylbenzylamine l-(−)-Malic Acid Salt through Classical Resolution” Org. Process Res. Dev., 2015, 12(19), pp 1954-1965.
C. Brandel, Y. Cartigny, N. Couvrat, E.M. Eusébio, J. Canotilho, S. Petit, G. Coquerel “Mechanisms of Reversible Phase Transitions in Molecular Crystals : Case of Ciclopirox” Chem. Mater., 2015, 27(18), pp 6360-6373.
C. Brandel, J. H. Ter Horst “Measuring Inductions Times and Crystal Nucleation Rates” Faraday Discuss., 2015, 179, pp 247-267.
C. Brandel, G. Gbabode, Y. Cartigny, C. Martin, G. Gouhier, S. Petit, G. Coquerel “Crystal Growth, Structure, and Polymorphic Behavior of an Ionic Liquid: Phthalate Derivative of N-Butyl, N-methylimidazolium Hexafluorophosphate” Chem. Mater., 2014, 26 (14), pp 4151-4162.
C. Brandel, Y. Amharar, J. Rollinger, U.J. Griesser, Y. Cartigny, S. Petit, G. Coquerel “Impact of Molecular Flexibility on Double Polymorphism, Solid Solutions and Chiral Discrimination during Crystallization of Diprophylline Enantiomers” Mol. Pharmaceutics, 2013, 10 (10), pp 3850–3861.
Orals :
"Crystal Growth Study of an Ionic Liquid: Polymorphism, Oiling-out and Complex Melting Behavior” C. Brandel, Y. Cartigny, F. Guillen, G. Gouhier, S. Petit, G. Coquerel. BIWIC 2013 (Bremer International Workshop for Industrial Crystallization), Septembre 18-20, 2013, Odense (Denmark).
"Complex Interactions in the Binary System between Enantiomers of Diprophylline” C. Brandel, Y.Amharar, J. Rollinger, U.J. Griesser, Y. Cartigny, S. Petit, G. Coquerel, PhandTA (Pharmacy and Thermal Analysis), Mai 6-7-8-9, 2012, Graz (Austria).
"Investigations in the Binary Phase Diagram between Diprophylline Enantiomers” C. Brandel, Y. Amharar, J. Rollinger, U.J. Griesser, Y. Cartigny, S. Petit, G. Coquerel, JEEP (Journée des équilibres entre phases) Mars 8-9-10, 2012, ROUEN (France).
Poster:
“Impact of molecular flexibility on the nucleation behaviour of Diprophylline enantiomers” C. Brandel, K. Viel, Y. Cartigny, S. Petit, G. Coquerel, Faraday Discussions (Nucleation - A Transition State to the Directed Assembly of Materials), Mars 30-31 et Avril 01, 2015, Leeds (UK).
« Versatility of Chiral Discrimination Mechanisms in the Crystal Forms of Diprophylline” C. Brandel, Y. Cartigny, S. Petit, G. Coquerel, ISIC (International Symposium on Industrial Crystallization), Septembre 16-19, 2014, Toulouse (France).
« Preparation of Chiral Organic Gels as New Soft Media for Single Crystal Growth” C. Brandel, S. Petit, G. Coquerel, BIWIC (Bremer Industrial Workshop for Industrial Crystallization), Septembre 10-12, 2014, Rouen (France).
« Subambient Solid-Solid Transformations in Ciclopirox Crystals » C. Brandel, Y. Cartigny, E. Eusebio, S.Petit, G. Coquerel, JCAT (Journee de Calorimetrie et d’analyse thermique) Mai 20-23, 2014, ROUEN (France).
« The Crystallization Behavior of a Solid Solution between two Enantiomers of the Active Pharmaceutical Ingredient Diprophylline” C. Brandel, Q. Viel, Y. Cartigny, G. Coquerel, JEEP (Journée des équilibres entre phases) Mars 26-28, 2014, Lyon (France).
"Application of Preferential Crystallization to a Chiral API in an Unfavorable Situation: Molecular Aspects” C. Brandel, Y. Amharar, Y. Cartigny, S. Petit, G. Coquerel, BIWIC 2013 (Bremer International Workshop for Industrial Crystallization), Septembre 18-20, 2013, Odense (Danemark).
"Molecular Mechanisms of Subambient Solid-Solid Phase Transitions in Ciclopirox Crystals” C.Brandel, Y. Cartigny, S. Petit, G. Coquerel, BIWIC 2013 (Bremer International Workshop for Industrial Crystallization), Septembre 18-20, 2013, Odense (Denmark).
“Crystallization Behavior and Polymorphism of a Phthalate Derivative of the N-butyl,Nmethylimidazolium Hexafluorophosphate Ionic Liquid” C. Brandel, Y. Cartigny, F. Guillen, G. Gouhier, S. Petit, G. Coquerel, ROSAM (Rouen Symposium on Advanced Materials) Juin 5-7, 2013, Rouen (France).
"Subambient Solid-Solid Transformations in Ciclopirox Crystals” C. Brandel, Y. Cartigny, S. Petit, G.Coquerel, JEEP (Journée des équilibres entre phases) Mars 8-9-10, 2012, ROUEN (France)
