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Mrs Charline GERARD Project in the lab : Chirality as a Probe for Crystal Nucleation Supervisor : Joop H. ter Horst Type of funding: Chair of excellence 02 35 52 00 00 |
Laboratoire SMS |
- Ph.D. in Biophysics (2014-2017, Aix Marseille University, ED 352, France), C.I.F.R.E.
CINaM – CNRS and IdRS
Microfluidic platform for optimization of crystallization conditions of proteins
- Master’s degree: Biochemistry, cells, therapeutic targets (2011-2013, University Paris-Diderot, France)
- First year master: Chemistry and materials (2010-2011, University Paris Est-Créteil, France)
Bachelor’s degree (License): Chemical and biological sciences (2007-2010, University Paris Est-Créteil, France)
- Post-doctorate (01/03/2020 to 31/08/2021)
Development and implementation of a microfluidic platform for solid state studies of API
Solid State group, Technology SERVIER (TES), Orléans, France
Supervisor: Dr. Philippe LETELLIER
- Post-doctorate: European Commission project AMECRYS (01/05/2018 to 31/01/2020)
Revolutionizing Downstream Processing of Monoclonal Antibodies by Continuous Template-Assisted Membrane Crystallization
Fundamental knowledge on selective mAbs crystallization in microfluidics
Continuous Manufacturing Crystallization (CMAC), Technical and Innovation Centre, Strathclyde University, Glasgow, UK
Supervisor: Prof. Joop H. TER HORST
- Research Engineer (01/10/2017 to 31/03/2018)
In charge for the biochemistry department
CINaM– CNRS, France
- « On the Aggregation and Nucleation Mechanism of the Monoclonal Antibody Anti-CD20 Near Liquid-Liquid Phase Separation (LLPS) »
E. PANTUSO, T.F. MASTROPIETRO, M.L. BRIUGLIA, C.J.J. GERARD, E. CURCIO, J.H. TER HORST, F.P. NICOLETTA, G. DI PROFIO, 2020. Scientific Reports, 10 (1), 1-14.
- « A chemical library to screen protein and protein-ligand crystallization using a versatile microfluidic platform »
C.J.J. GERARD, G. FERRY, L.M. VUILLARD, J.A. BOUTIN, N. FERTE, R. GROSSIER, N. CANDONI, S. VEESLER, 2018. Crystal growth & design, 18 (9), 5130-5137.
- « Crystallization via tubing microfluidics permits both in situ and ex situ X-ray diffraction »
C.J.J. GERARD, G. FERRY, L.M. VUILLARD, J.A. BOUTIN, L.M.G. CHAVAS, T. HUET, N. FERTE, R. GROSSIER, N. CANDONI, S. VEESLER 2017. Acta Crystallographica Section F, 73 (10), 574-578.
- « Microfluidic platform for optimization of crystallization conditions »
S. ZHANG, C.J.J. GERARD, A IKNI, G. FERRY, L.M. VUILLARD, J.A. BOUTIN, N. FERTE, R. GROSSIER, N. CANDONI, S. VEESLER 2017. Journal of Crystal Growth, 472, 18-28.
- « Plateforme microfluidique pour optimiser la cristallisation en solution »
C.J.J. GERARD, S. ZHANG, A. IKNI, G. FERRY, L.M. VUILLARD, J.A. BOUTIN, N. FERTE, R. GROSSIER, N. CANDONI, S. VEESLER Congress Cristal-8, Rouen, 2016. Récents Progrès en Génie des Procédés, Numéro 108 – 2016, ISSN: 1775-335X; ISBN: 978-2-910239-83-1, Ed. SFGP, Paris, France
- 22nd American Conference on Crystal Growth and Epitaxy ACCGE-22, (Online event)
02-04/08/2021
Invited presentation: « Microfluidic set-up for solid-state studies of Active Pharmaceutical Ingredients directly from powder »
C.J.J. Gerard, G. Peybernès, R. Grossier, F. Villard, P. Letellier, N. Candoni, S. Veesler
- BIWIC2019 International Workshop on Industrial Crystallization (Rayong, Thailand)
26-28/08/2019
Oral presentation: « Microfluidics as a tool to study protein heterogeneous nucleation»
C.J.J. Gerard, M.L. Briuglia, S. Morais, D. Lamprou, J.Y.Y. Heng, J.B. Salmon, J.H. ter Horst
- CMAC open days (Glasgow, UK)
25-26/10/2018
Poster session: « Multiscale template-assisted protein crystallization »
C.J.J. Gerard, M.L. Briuglia, S. Morais, J.B. Salmon, D. Lamprou, J.H. ter Horst
- 20th International Symposium on Industrial Crystallization ISIC20 (Dublin, Ireland)
03-06/09/2017
Oral presentation: « Tubing microfluidic: From crystallization to X-ray diffraction »
C.J.J. Gerard, S. Zhang, A. Ikni, G. Ferry, L.M. Vuillard, J.A. Boutin, L. Chavas, T. Huet, N. Ferté, R. Grossier, N. Candoni, S. Veesler
- 16th International Conference on Crystallization of Biological Macromolecules ICCBM16 (Prague, Czech Republic)
02-07/07/2016
Oral presentation: « Microfluidic platform for optimization of crystallization conditions »
C.J.J. Gerard, S. Zhang, A. Ikni, G. Ferry, L.M. Vuillard, J.A. Boutin, N. Ferté, R. Grossier, N. Candoni, S. Veesler
- Cristal-8 (Rouen, France)
26-27/05/2016
Oral presentation: « Plateforme microfluidique pour optimiser la cristallisation en solution »
C.J.J. Gerard, S. Zhang, A. Ikni, G. Ferry, L.M. Vuillard, J.A. Boutin, N. Ferté, R. Grossier, N. Candoni, S. Veesler
- International Crystallization Schools (Granada, Spain)
29/05-03/06/2016
Invited presentation: « Droplet-based Microfluidics in the framework of crystallization studies »
R. Grossier, N. Candoni, Z. Hammadi, N. Ferté, S. Zhang, C.J.J. Gerard, A. Ikni, R. Morin, S. Veesler
- Crystallize COST Action Meeting (Berlin, Germany)
23-24/11/2015
Poster session: « Optimization and screening of protein crystallization conditions: Development of a microfluidic tool »
C.J.J. Gerard, S. Zhang, N. Ferté, R. Grossier, Z. Hammadi, N. Candoni, S. Veesler, L.M. Vuillard, G. Ferry, O. Nosjean, J.A. Boutin
